Zestoretic 5mg/12.5 mg

Generic Name: hydrochlorothiazide and lisinopril
Brand Names: Prinzide, Zestoretic

Zestoretic is a combination of a diuretic and an ACE inhibitor indicated to treat high blood pressure. Zestoretic is a combination of two drugs. Hydrochlorothiazide is a thiazide diuretic medication while Lisinopril belongs to the class of drugs called ACE inhibitors. The first prevents body from absorbing too much salt, which can cause fluid retention, and the second lowers blood pressure and also relieves symptoms of fluid retention.estoretic is a combination of a diuretic and an ACE inhibitor indicated to treat high blood pressure.

Important information Zestoretic
Do not use Zestoretic if you are unable to urinate.
You should not use Zestoretic if you are allergic to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).
Before taking Zestoretic, tell your doctor if you have kidney disease (or are on dialysis), liver disease, congestive heart failure, gout, lupus, diabetes, or an allergy to sulfa drugs.
Lisinopril can cause birth defects in the baby if you take the medication during pregnancy. Do not use Zestoretic without telling your doctor if you are pregnant or planning a pregnancy. Avoid the regular use of salt substitutes in your diet, and do not take potassium supplements while taking Zestoretic, unless your doctor has told you to.
Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking other diuretics (water pills). Follow your doctor's instructions about the type and amount of liquids you should drink while taking Zestoretic. Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Precautions
Avoid drinking alcohol. Avoid salt substitutes containing potassium. If you have disorders of liver or kidney, lupus, asthma, gout, diabetes, congestive heart failure or pregnant consult your doctor first than to take Zestoretic. While you are taking Zestoretic, your blood pressure will need to be checked regularly.

Contraindications
Anuria, hypersensitivity to the components of Zestoretic, in patients who had angioedema (swelling of face, extremities, eyes, lips, tongue, difficulty in swallowing or breathing) in their history.

Possible side effects
Seek for immediate medical help if such symptoms are observed while taking Zerstoretic: high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling), low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling), thirst, nausea, vomiting, dry mouth, drowsiness, skin rash jaundice urinating less than usual swelling, weight gain and any serious symptom of allergy (hives, swelling of your face, lips, tongue, or throat).